part 1. Explicating addiction. The puzzle of addiction ; Diagnosing disagreement ; Heterogeneity ; Values and person's own good ; Comparisons and objections
part 2. Shifting the paradigm. Introduction to part II ; Compulsion in rats and humans ; The idea of irresistible desire ; Brain pathology ; The cause
part 3. Solving the puzzle. Introduction to part III ; Self-medication ; Self-harm ; Self-identity ; Denial ; Problems of control ; Craving
part IV. Ethics and relationships. Introduction to part IV ; The rescue-blame trap ; Responsibility ; Blame ; Responsibility without blame for addiction